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GMP grade polysorbates for Nucleic Acid Delivery

Polysorbates are non-ionic surfactants and emulsifiers commonly used in the pharmaceutical industry to promote API absorption and prevent the formation of aggregates and precipitation.

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Polysorbates

Polysorbates such as Tween are also commonly used to formulate lipid-based gene carriers. Playing a key role in these formulations as emulsifiers and stabilisers polysorbates also have an active role in the integration of DNA and therefore promote gene expression1.

We have a wide offering of compendial, high purity and Super Refined™ polysorbates to suit your formulation needs, explore our offering below! 

Tween 20 HP Featured

Tween™ 20 HP

Tween 20 HP is a low moisture, low peroxide, high performance version designed for parenteral use. Tween 20 HP is an excellent O/W emulsifier, solubiliser and wetting agent. Recommended topical usage...
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Tween 80 HP Featured

Tween™ 80 HP

Tween 80 HP is a low moisture, low peroxide, high performance grade designed for parenteral use. Tween 80 HP works as an O/W emulsifier, solubiliser and wetting agent. This grade exceeds standards...
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Super Refined Polysorbate 20 Featured

Super Refined™ Polysorbate 20

Super Refining removes impurities, preventing adverse interactions with APIs and enhancing the stability of pharmaceutical formulations. Super Refined Polysorbates offer the complete solution when...
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Super Refined Polysorbate 80 Featured

Super Refined™ Polysorbate 80

Super Refined Polysorbates solubilise and stabilise the most sensitive active ingredients across dosage forms including injectable and oral. Super Refining removes impurities (including primary and...
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Why partner with us?

Support from concept to commercial

It starts with having the leading lipid technology experts in synthesis and formulation and approaching the discovery process in a collaborative nature, then having the expertise to transfer those learnings into a GMP manufacturing environment to support clinical development. And finally, having the commercial production capability to support launch and commercial supply.

Our full range of services include process chemistry, scale-up manufacturing, supply chain management with analytical and regulatory requirements. Our experienced staff of chemists and lipid analysts are ready to meet your development needs with pre-clinical through phase III and commercial launch, speak to one of our experts today!

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Lipid supporting services

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CDMO cGMP manufacturing

CDMO project management from R&D through to commercialization. Contract manufacturing of proprietary lipid products.
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Custom synthesis

Synthesis of research use materials for a variety of applications. Custom synthesis of reference standards or impurities.
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Formulation

Development of a suitable formulation for lipid-based delivery systems. Custom lipid blends for use in delivery or diagnostic applications.
1. Huang, Y. et al. (2011) ‘Polysorbate cationic synthetic vesicle for gene delivery’, Journal of Biomedical Materials Research Part A, 96A(3), pp. 513–519. doi:10.1002/jbm.a.32999.