Super Refined™ Oleyl Alcohol

Super Refined Oleyl Alcohol is a highly purified lipid-based solubiliser and skin penetration enhancer that acts as a wetting agent and active dispersant in topical creams and ointment applications. Super Refined Oleyl Alcohol is a lipophilic enhancer that promotes skin penetration by means of bilayer disruption and disordering. It assists the percutaneous absorption of water-soluble and oil-soluble drugs by means of partial leaching of the epidermal lipids. The bilayer architecture of the stratum corneum lipids is disorganised by the introduction of phase separation and direct disruption of a proper lamellar arrangement. This results in the improvement of the skin’s reception for transdermal and transfollicular penetration. The proprietary Super Refining process removes impurities without altering the chemical composition of the excipient. This reduces the potential for adverse interactions between the excipient and the API, enhancing active stability and efficacy.