Macrogol Lauryl Ether 9 (Ph. Eur.), Polyoxyl 9 Lauryl Ether (USP)
Virodex™ TXR-1 is a readily biodegradable, nonionic surfactant for viral inactivation and cell lysis, meeting the needs of biopharmaceutical applications as an effective and safe replacement for the traditional detergent, Triton™ X-100. As a next-generation, sustainable detergent, Virodex™ TXR-1, along with its excellent biological compatibility, is recommended to be used in the efficient biomanufacturing of recombinant proteins such as monoclonal antibodies, as well as plasma-derived therapies, viral vector-based therapies and more.
Key Benefits
- Readily biodegradable, sustainable and REACH-compliant
- Meets cGMP EXCiPACT standards for the highest product quality in biopharmaceutical manufacturing
- Compendial grade, in compliance with USP and Ph. Eur. monographs
- Known use of chemistry by industry for viral inactivation, as well as known injectable use1
- Manufactured in a facility that sources all renewable electric, producing zero scope II emissions
- No risk of nitrosamine formation
- Improved biologic quality and lower biomanufacturing risk, enabling faster speed to market
- Equivalent virus inactivation and cell lysis characterization to Triton™ X-100, with better performance than three market alternatives
- Available pack sizes: 1 kg, 3 kg and 25 kg
- Comes with additional COA testing: bacterial endotoxin, Total Aerobic Microbial Count (TAMC), and Total Yeast and Mould Count (TYMC)
Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow.
1Hunter, A. K. et al. Identification of compendial nonionic detergents for the replacement of Triton X‐100 in Bioprocessing. Biotechnology Progress 38, (2022).