Saturated free fatty acids have been associated with the formation of visible and sub-visible particles in cases where hydrolytic degradation of polysorbate 20 occurs. Tween™ 20 HP LSA is a highly purified polysorbate 20 that has been designed to provide functional equivalence as a surfactant whilst reducing the associated risk of visible and sub-visible particle formation in protein formulations. This has been achieved through a very highly controlled fatty acid distribution with lower content of long chain saturated fatty acids.
Product details
Pharmacopoeia compliance
- ChP
- JP/JPE
- Ph. Eur.
- USP/NF
Chemical group
- Polysorbate
- Sorbitan ester
Administration route
- Oral
- Parenteral
- Topical
Market application
- Human pharmaceutical
- Veterinary health
Functions
- Emulsifier
- Excipient
- Nonionic surfactant
- Wetting agent
Physical form
- Clear yellow liquid