ALC-0159
Methoxypolyethyleneglycoloxy(2000)-N,N-ditetradecylacetamide
ALC-0159 is a polyethylene glycol (PEG)-lipid conjugate also called a PEGylated lipid. ALC-0159 is a lipid excipient that can be used to form lipid nanoparticles (LNPs).
PEGylated lipids allow increased circulation times of LNP delivery systems due to their ability to circumvent systemic clearance.
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It starts with having the leading lipid technology experts in synthesis and formulation and approaching the discovery process in a collaborative nature, then having the expertise to transfer those learnings into a GMP manufacturing environment to support clinical development. And finally, having the commercial production capability to support launch and commercial supply.
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