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DSPC

2,3-Dioleoyl-glycero-1-phosphocholine

Phosphatidylcholines (PCs), also referred to as neutral lipids, form the exterior layer of the delivery system.

DSPC is the most common PC derivative used in lipid nanoparticles (LNP) due to its high transition temperature (55C) which allows it to prevent the premature breakdown of the LNP in biological systems.

DSPC lipid nanoparticle structure

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Nucleic Acid delivery croda pharma

DOPC

Phospholipid
Nucleic acid

DOPE

Phospholipid

Lipid supporting services

CDMO cGMP manufacturing

CDMO project management from R&D through to commercialization. Contract manufacturing of proprietary lipid products.

Custom synthesis

Synthesis of research use materials for a variety of applications. Custom synthesis of reference standards or impurities.

Formulation

Development of a suitable formulation for lipid-based delivery systems. Custom lipid blends for use in delivery or diagnostic applications.
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Why partner with us?

Support from concept to commercial

It starts with having the leading lipid technology experts in synthesis and formulation and approaching the discovery process in a collaborative nature, then having the expertise to transfer those learnings into a GMP manufacturing environment to support clinical development. And finally, having the commercial production capability to support launch and commercial supply.

Our full range of services include process chemistry, scale-up manufacturing, supply chain management with analytical and regulatory requirements. Our experienced staff of chemists and lipid analysts are ready to meet your development needs with pre-clinical through phase III and commercial launch, speak to one of our experts today!

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